---
title: Standard - Correlation-Based
slug: standard-correlation-based
createdAt: 2026-04-27T14:07:09.736Z
---

The linear correlation between each gene pair was computed across all relevant datasets and samples, and further statistically assessed resulting in a normalized T-Value. The normalized T-Value quantifies how consistently the association between two genes is conserved across all included datasets, within the user-defined tissue and biological context (higher T-Values indicate stronger gene–gene associations). This measure incorporates dataset size, assigning greater weight to larger studies. Only gene pairs found in at least 15 datasets were included in the final displayed network. Mavatar Discovery users can adapt how many strong associations (neighbors) to include in the outcome network by adapting the distance and neighbor parameters within the Generate Graph window. Importantly, only positive correlations are considered in the analysis.